Random Mutations = Spontaneous Generation

Author: jack     03 16th, 2010 in enart.abczj.com     edit

  • The paper at Nature Precedings

    http://precedings.nature.com/documents/553/version/1

    puts "random mutations" in the same category as "spontaneous generation".

    The shuffling of polymorphisms, going from one to many in the Concurrent paper, and going from many to one in the Nigerian human HA sequences clearly shows that de novo "random mutations" are rare, and most of the new acquisitions are of pre-existing polymorphisms acquired via recombination.

    Next week's paper will walk the reader through the data, but the bottom line is clear - "random mutations" are history, and the fact that they held such sway for so long will be a constant source of amazement and amusement for science students for many generations to come.


  • Another knowledgeable 'flubie' was lamenting the lack of meaningful research being published about H5N1. As in, the most recent research indicating that reassortment can take place anytime of the year, is a real 'No duh!'

    Dr. Niman, I was wondering if your recent publications haven't pre-empted a number of papers that would have been published, but assumed random mutation as a fundamental premise.

    Is it possible that your papers have served as the equivalent of opening the bidding with a bid 3-Spades in a bridge game, and have pre-empted the bidding?
    No, the one club opening will remain popular.

    I was at Options VI and the hand wavers are very used to waving hands. They will continue.


  • Another knowledgeable 'flubie' was lamenting the lack of meaningful research being published about H5N1. As in, the most recent research indicating that reassortment can take place anytime of the year, is a real 'No duh!'

    Dr. Niman, I was wondering if your recent publications haven't pre-empted a number of papers that would have been published, but assumed random mutation as a fundamental premise.

    Is it possible that your papers have served as the equivalent of opening the bidding with a bid 3-Spades in a bridge game, and have pre-empted the bidding?


  • The question is will they respond or just pass, it is never much of a game if the opposition are not interested in engaging, perhaps they just dont have the point count. Dr. Niman needs a partner to weigh in with a 4NT reply, again not much of a game without an active bidder sitting opposite you. It was good to see the last paper co-authored.
    I don't think 4NT is in the cards.


  • lol

    You might win someone over.


  • The question is will they respond or just pass, it is never much of a game if the opposition are not interested in engaging, perhaps they just dont have the point count. Dr. Niman needs a partner to weigh in with a 4NT reply, again not much of a game without an active bidder sitting opposite you. It was good to see the last paper co-authored.
    The Options VI paper has lots of authors (now if I could get each of them to vote!)

    http://precedings.nature.com/documents/553/version/1

    but the meeting was almost all handwaving. I have been to lots of scientific meetings, but have never seen anything quite like Options VI.


  • The question is will they respond or just pass, it is never much of a game if the opposition are not interested in engaging, perhaps they just dont have the point count. Dr. Niman needs a partner to weigh in with a 4NT reply, again not much of a game without an active bidder sitting opposite you. It was good to see the last paper co-authored.







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